Sophie Cousin Selected Research

molibresib

1/2022	Safety, pharmacokinetic, pharmacodynamic and clinical activity of molibresib for the treatment of nuclear protein in testis carcinoma and other cancers: Results of a Phase I/II open-label, dose escalation study.
4/2020	Phase 1 Study of Molibresib (GSK525762), a Bromodomain and Extra-Terminal Domain Protein Inhibitor, in NUT Carcinoma and Other Solid Tumors.

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Sophie Cousin Research Topics

Disease

18	Neoplasms (Cancer) 01/2022 - 04/2014
8	Sarcoma (Soft Tissue Sarcoma) 01/2022 - 02/2016
4	Nausea 01/2022 - 04/2020
4	Fatigue 01/2022 - 01/2020
3	Carcinoma (Carcinomatosis) 01/2022 - 04/2020
3	Breast Neoplasms (Breast Cancer) 01/2022 - 07/2012
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 01/2019
3	Neoplasm Metastasis (Metastasis) 01/2019 - 04/2017
2	Brain Neoplasms (Brain Tumor) 01/2022 - 01/2019
2	Thrombocytopenia (Thrombopenia) 01/2022 - 04/2020
2	Vomiting 01/2021 - 04/2020
2	Leiomyosarcoma 04/2017 - 02/2016
1	Triple Negative Breast Neoplasms 01/2022
1	Biliary Tract Neoplasms (Biliary Tract Cancer) 01/2022
1	Lung Neoplasms (Lung Cancer) 01/2022
1	Neutropenia 01/2022
1	Prostatic Neoplasms (Prostate Cancer) 01/2022
1	Thymoma (Thymic Carcinoma) 01/2022
1	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 01/2022
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2022
1	Alopecia (Baldness) 01/2021
1	Disease Progression 01/2021
1	Colorectal Neoplasms (Colorectal Cancer) 01/2021
1	Tertiary Lymphoid Structures 01/2021
1	Sarcopenia 12/2020
1	Dysgeusia (Parageusia) 04/2020
1	Anemia 04/2020
1	Diarrhea 04/2020
1	Stomatitis 01/2020
1	Hypertension (High Blood Pressure) 01/2020
1	Weight Loss (Weight Reduction) 01/2020
1	Cholangiocarcinoma 01/2018
1	Adenosarcoma of the uterus 01/2018
1	Carcinogenesis 09/2017
1	Autoimmune Diseases (Autoimmune Disease) 09/2016
1	Melanoma (Melanoma, Malignant) 09/2016

Drug/Important Bio-Agent (IBA)

7	Immune Checkpoint InhibitorsIBA 01/2021 - 09/2016
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2018
3	Tyrosine Kinase InhibitorsIBA 01/2022 - 01/2020
3	AntibodiesIBA 01/2022 - 09/2017
3	Pharmaceutical PreparationsIBA 01/2022 - 04/2014
2	PlatinumIBA 01/2022 - 01/2022
2	regorafenibIBA 01/2022 - 01/2021
2	B7-H1 AntigenIBA 01/2022 - 01/2022
2	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2017
2	Nuclear Proteins (Protein, Nuclear)IBA 01/2022 - 04/2020
2	avelumabIBA 01/2022 - 01/2021
2	molibresibIBA 01/2022 - 04/2020
2	AnthracyclinesIBA 01/2021 - 02/2019
2	Ifosfamide FDA LinkGeneric 01/2021 - 04/2017
1	durvalumabIBA 01/2022
1	lenvatinibIBA 01/2022
1	pembrolizumabIBA 01/2022
1	Anaplastic Lymphoma KinaseIBA 01/2022
1	NivolumabIBA 01/2022
1	TrabectedinIBA 01/2022
1	Alanine (L-Alanine)FDA Link 01/2022
1	Essential Amino AcidsIBA 01/2022
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2022
1	EnzymesIBA 01/2022
1	Exonucleases (3' 5' Exonuclease)IBA 01/2022
1	InterferonsIBA 01/2022
1	KynurenineIBA 01/2022
1	Estrogen ReceptorsIBA 01/2022
1	Tryptophan (L-Tryptophan)FDA Link 01/2022
1	Tryptophan Oxygenase (Tryptophan 2,3 Dioxygenase)IBA 01/2022
1	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 01/2022
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 01/2022
1	lorlatinibIBA 01/2022
1	nintedanibIBA 01/2021
1	cyclopropapyrroloindoleIBA 12/2020
1	Sunitinib (Sutent)FDA Link 01/2020
1	cabozantinibIBA 01/2020
1	Imatinib Mesylate (Gleevec)FDA Link 01/2020
1	GadoliniumIBA 02/2019
1	thiamine triphosphorate (TTP)IBA 10/2018
1	Biological ProductsIBA 01/2018
1	Programmed Cell Death 1 ReceptorIBA 01/2018
1	Lapatinib (GW572016)FDA Link 01/2018
1	Trastuzumab (Herceptin)FDA Link 01/2018
1	InterleukinsIBA 09/2017
1	Macrophage Colony-Stimulating FactorIBA 09/2017
1	LigandsIBA 09/2017
1	Doxorubicin (Adriamycin)FDA LinkGeneric 04/2017
1	Trinitrotoluene (TNT)IBA 04/2017
1	Formaldehyde (Formol)FDA Link 01/2017
1	ParaffinIBA 01/2017
1	IpilimumabIBA 09/2016
1	SteroidsIBA 09/2016

Therapy/Procedure

7	Drug Therapy (Chemotherapy) 01/2022 - 07/2012
6	Immunotherapy 01/2022 - 09/2016
3	Neoadjuvant Therapy 01/2021 - 12/2018
3	Therapeutics 12/2020 - 04/2017
2	Drug Tapering 01/2022 - 01/2020
1	Castration 01/2022
1	Aftercare (After-Treatment) 01/2020
1	Salvage Therapy 10/2019
1	Radiotherapy 10/2019
1	Time-to-Treatment 10/2018
1	Combination Drug Therapy (Combination Chemotherapy) 04/2017